Micheal Scofield (Wentworth Miller) has been hinting the possibility of season 6. Speaking to Digital Spy, at San Diego Comic-Con in 2016, Wentworth said that he was open to another season. He said that there was always room for more as long as the story was worth telling, ” as long as it feels justified and cool and edgy.” he said.
Seems like Prison Break creator Paul Scheuring is giving out a lot of information lately on his twitter account. in a recent twit Scheuring just expressed his interest to do a Season 6 for Prison Break. And a fan asked about the possibility of Mahone (William Fichtner) returning, he had a promising response.
@prisonersbreak Mahone: S6?
— Paul T. Scheuring (@paultscheuring) February 21, 2017
Prison Break Season 5 will premiere on Tuesday, April 4 at 9 p.m. ET on FOX.